Cancer Treatment

Not all neutropenia as needs to be treated. Especially, when neutropenia is chronic and there are no chronic or recurrent infections, it becomes difficult to advocate for indefinite treatment with G-CSF. Early case reports suggested that G-CSF can modulate autoimmune processes in autoimmune neutropenia(AIN) but that has not been proven. The issue is complicated by [...]

 Docetaxel, a taxane that promotes polymerization of tubules and inhibits depolymerization of microtubules, has shown in vitro and in vivo antitumor effects on human gastric cell lines and gastric cancer xenografts. These antitumor effects have led to the evaluation of docetaxel as a single agent and in combination with other agents and modalities in patients [...]

Sacroiliac injection can be used diagnostically or therapeutically. There are no prospective a controlled trials to support this procedure. Most support cards from case reports or case series. Case series are unreliable evidence due to the variable natural history of back pain, the presence of confounders of outcome, and the potential for a placebo effect. [...]

Sacroiliac injection can be used diagnostically or therapeutically. There are no prospective a controlled trials to support this procedure. Most support cards from case reports or case series. Case series are unreliable evidence due to the variable natural history ofback pain, the presence of confounders of outcome, and the potential for a placebo effect. Ingeneral, [...]

While a combined resection of rectal cancer and partial hepatectomy are well established, the same is not the case for anal cancer. Metastatic anal cancer is not well studied in regard to combined resection. NCCN recommends only 5FU and cisplatin or cisplatin for metastatic anal cancer. A recent review states: " Metastatic disease develops in [...]

Charged-particle beams consisting of protons or helium ions are a type of particulate radiation therapy that contrast with conventional electromagnetic (i.e., photon) radiation therapy due to the unique properties of minimal scatter as the particulate beams pass through the tissue, and deposition of the ionizing energy at a precise depth (i.e., the Bragg Peak). Thus [...]

Transverse myelitis is an inflammatory condition of the spinal cord, which affects thel covering nerve cell fibers (myelin). Transverse myelitis causes diminished or absent sensation below the injury. The disrupted transmission of nerve signals due to transverse myelitis can cause pain or other sensory problems, weakness or paralysis of muscles, or bladder and bowel dysfunction. Transverse meylitis [...]

The use of MRI before breast surgery is increasing based on reports that show that MRI can detect previously unknown foci of breast cancer in a substantial number of women with a new diagnosis of breast cancer. However, some argue that MRI will increase the proportion of mastectomy. Since breast conservation surgery combined with radiation therapy [...]

ALL is the most common cancer diagnosed in children and young adults represents almost 25% of cancers in children younger than 15 years. Complete remission of disease is now typically achieved with pediatric chemotherapy regimens in approximately 95% of children with ALL, with up to 85% long-term survival rates. Young adults are treated as children, [...]

Tamoxifen has different effects on different tissues. Whereas at blocks estrogen in the breast, it has pro- estrogenic effects on bone and in the uterus. It can cause dysfunctional uterine bleeding and endometrial thickening and very rarely, superficial, easily treatable, endometrial cancer and sarcoma.  In a review of all NSABP breast cancer treatment trials, the rate [...]